I noticed a couple of the thour pictures being put into the anatomical nonsense tag, and I'm not sure if they actually qualify? The wiki page for AN specifies a "total disregard both for realistic anatomy and for the usual stylistic deviations therefrom", and I'm pretty sure that the imploded face has been a common way to stylize a strong reaction to sourness since at least the classic looney tunes era, if not even earlier.